Ready-to-use
Density gradients for sperm selection in human assisted reproduction procedures
Why Sil-Select Plus?
Sil-Select Plus is our home made new, improved and ready-to-use gradient system for semen preparation. The following gradients are available:
- Sil-Select Plus Upper layer (45%)
- Sil-Select Plus 80%
- Sil-Select Plus Lower layer (90%)
Sil-Select Plus gradients consist of silane-coated colloidal sicila particles suspended in HEPES-buffered Earle’s balanced salts solution, and as from batch FP18SIP20 supplemented with 0.4 – 2.2g/l human serum albumin.
Extensive testing during the design of the product has shown it to be non-cytotoxic and non-irritant with a non-significant allergenic potential.
Sil-Select Plus is produced from raw colloidal silica, so we have full control over each step in the production process. We have developed a very accurate purification system which results in a very clean product with endotoxin levels below 0.5EU/mL.
The Sil-Select Plus density gradient system (45%-90%) consists of a Sil-Select Plus Upper Layer (45%) and a Sil-Select Plus Lower Layer (90%).
We also offer Sil-Select Plus in an 80% dilution for use in IVF procedures.
| pH | 7.2 – 7.9 (7.2-7.6 at release) |
| Osmolality | 280-310mOsm/kg (Upper Layer) 290-330mOsm/kg (Lower Layer) 290-330mOsm/kg (80%) |
| Sterility | Sterile |
| Endotoxine | < 0.5 EU/mL |
| Sperm Survival test | ≥ 80% survival after 4 hours exposure of density selected spermatozoa to the test medium; and ≥ 75% survival after 24 hours exposure of density selected spermatozoa to the test medium |
| Density | 1.1050-1.1150g/mL (Lower Layer) 1.097-1.107g/mL (80%) |
| Viscosity in cP (25°C) | <1.65cP (Lower Layer, 80%) |
| Albumin | FDA (USA) and EMA (Europe) compliant |
| In-use stability | Can be used safely up to 7 days after opening, when sterile conditions are maintained and the products are stored at 2-8°C |
SIP008 : Sil-Select Plus – 8 preparations*
SIP016 : Sil-Select-Plus – 16 preparations*
*include bottles Sil-Select Plus Sperm Washing/Insemination medium
SIP020: Sil-Select Plus – Lower Layer 1 x 20ml and Upper Layer 1 x 20ml
SIP050 : Sil-Select Plus – 2 x 50mL
SIP100 : Sil-Select Plus – 2 x 100mL
SIP80_100 : Sil-Select Plus 80% – 100mL
Contact us about your FertiPro needs
We supply the full range of FertiPro products. Call us on 0114 224 2257 to discuss your order. 96% of our orders are despatched within 48 hours.